Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations
نویسندگان
چکیده
BACKGROUND Concern has recently emerged regarding the safety of natural health products (NHPs)-therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins and many take herbal agents, this study endeavored to determine levels of toxic element contamination within a range of NHPs. METHODS Toxic element testing was performed on 121 NHPs (including Ayurvedic, traditional Chinese, and various marine-source products) as well as 49 routinely prescribed pharmaceutical preparations. Testing was also performed on several batches of one prenatal supplement, with multiple samples tested within each batch. Results were compared to existing toxicant regulatory limits. RESULTS Toxic element contamination was found in many supplements and pharmaceuticals; levels exceeding established limits were only found in a small percentage of the NHPs tested and none of the drugs tested. Some NHPs demonstrated contamination levels above preferred daily endpoints for mercury, cadmium, lead, arsenic or aluminum. NHPs manufactured in China generally had higher levels of mercury and aluminum. CONCLUSIONS Exposure to toxic elements is occurring regularly as a result of some contaminated NHPs. Best practices for quality control-developed and implemented by the NHP industry with government oversight-is recommended to guard the safety of unsuspecting consumers.
منابع مشابه
Adverse Events Associated with Metal Contamination of Traditional Chinese Medicines in Korea: A Clinical Review
This study was performed to review studies carried out in Korea reporting toxic reactions to traditional Chinese medicines (TCMs) as a result of heavy metal contamination. PubMed (1966-August 2013) and International Pharmaceutical Abstracts (1965-August 2013) were searched using the medical subject heading terms of "Medicine, Chinese Traditional," "Medicine, Korean Traditional," "Medicine, Trad...
متن کاملDetection of Microbial Contamination in quality control of Ophthalmic Preparations by PCR
INTRODUCTION Contamination of pharmaceutical preparations by micro-organisms continues to be a matter of concern to the pharmacists. From the beginning it has been an official requirement that parenteral preparations shall be sterile. More recently a number of serious infections in the eye in Britain and elsewhere have resulted in the further requirement that all preparations used in the eye sh...
متن کاملEvaluation of microbial content of some sunscreen creams in Iran’s market
The risk of microbial contamination in the cosmetic products especially in smuggled preparations and transmission of it to consumers is very high. In this study, the microbial content and the pollution of some sunscreen creams in the market and one sample in official market as witness were evaluated. The microbial content (bacterial total count, fungal count, and presence of Pseudomon asaerogin...
متن کاملThe Benefits and Risks of Consuming Brewed Tea: Beware of Toxic Element Contamination
Background. Increasing concern is evident about contamination of foodstuffs and natural health products. Methods. Common off-the-shelf varieties of black, green, white, and oolong teas sold in tea bags were used for analysis in this study. Toxic element testing was performed on 30 different teas by analyzing (i) tea leaves, (ii) tea steeped for 3-4 minutes, and (iii) tea steeped for 15-17 minut...
متن کاملRole of natural products in mitigation of toxic effects of methamphetamine: A review of in vitro and in vivo studies
Objective: Methamphetamine (METH) increases dopamine, norepinephrine and serotonin concentrations in the synaptic cleft, and induces hyperactivity. The current management of acute METH poisoning relies on supportive care and no specific antidote is available for treatment. The main objective of this review was to present the evidence for effectiveness of the herbal medicine in ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2012